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Next step: Endocrine workup including morning cortisol and ACTH levels

Results in real life can vary depending on individual factors, adherence and the kind of support people have in place

Cosman R, Brown CS, DeBraganca KC, Khasraw M

In June 2024, Pfizer announced that the once-daily formulation did not meet efficacy and tolerability targets and would not progress to Phase 3 trials for obesity treatment

Yang L, Wang H, Yang X, Wu Q, An P, Jin X, et al

Our findings suggest that the guarana-selenium-carnitine supplementation can modulate oxidative stress levels, but further studies are necessary to explore the neuro-biological consequences of consuming the supplement